Selank
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) and a stabilized analog of the endogenous tetrapeptide Tuftsin. In the field of neuroscience and neuropsychopharmacology, Selank is researched for its unique ability to provide anxiolytic (anti-anxiety) effects without the sedative or addictive properties associated with traditional benzodiazepines. Its mechanism involves modulating the expression of Interleukin-6 (IL-6) and influencing the metabolism of serotonin and other monoamine neurotransmitters. Furthermore, Selank is a critical tool for studying the upregulation of Brain-Derived Neurotrophic Factor (BDNF) in the hippocampus, making it a primary focus for research into cognitive enhancement and stress-response regulation.
Our Selank is synthesized in an ISO 9001:2015 certified and GMP-grade manufacturing environment. By utilizing advanced Solid-Phase Peptide Synthesis (SPPS) and rigorous multi-stage HPLC purification, we achieve an ultra-high chemical purity of ≥99%. This meticulous production standard ensures the peptide is free from truncated fragments and residual chemical reagents, providing the high-fidelity results required for sensitive behavioral studies and neurotransmitter signaling analysis.
Research Applications & Mechanisms
Neurotransmitter Regulation
Investigating the influence of Selank on GABAergic signaling and monoamine metabolism to study its non-sedative anxiolytic pathways.
Neurotrophic & Cognitive Support
Researching the upregulation of BDNF mRNA expression and its impact on synaptic plasticity, memory consolidation, and learning focus.
Immunomodulatory Signaling
Studying the peptide’s role in balancing the cytokine profile, specifically its influence on IL-6 levels during experimental stress models.
Stability & Proteolytic Resistance
Exploring the role of the Pro-Gly-Pro sequence in preventing enzymatic degradation, allowing for extended bioactivity in various research media.
Technical Specifications
| Parameter | Laboratory Standard |
| Compound | Selank (Tuftsin Analog) |
| Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro |
| Purity (HPLC) | ≥99% (Pharmaceutical Grade) |
| Physical Appearance | Fine, Smooth & Flat Lyophilized Cake |
| Molecular Weight | 751.9 Da |
| Concentration | Available in 5mg / 10mg vials |
| Solubility | Highly Soluble in Water (Aqueous) / Bacteriostatic Water |
| Batch Control | MS & HPLC Analysis Verified |
Key Features & Quality Assurance
Pharmaceutical-Grade Lyophilization
Our proprietary vacuum-sealing process ensures the Selank powder surface is perfectly smooth, flat, and delicate. This uniform “cake” structure ensures rapid, clear reconstitution and maintains the molecular integrity of the peptide during long-term storage.
High-Fidelity Synthesis
Every batch undergoes strict Mass Spectrometry (MS) to confirm the exact amino acid sequence, ensuring that the critical Tuftsin-derived domains remain fully functional for receptor-binding research.
Reconstitution & Storage
Reconstitution Guide
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Preparation: Allow the vial to reach room temperature. Centrifuge for 30-60 seconds to ensure the Selank cake is at the base.
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Solvent: Reconstitute with Sterile Water or Bacteriostatic Water.
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Technique: Gently introduce the diluent against the vial wall. DO NOT SHAKE; swirl gently until the solution is clear and transparent.
Storage Protocols
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Long-term: Store at -20°C (Maintains potency for up to 24 months).
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Short-term: Stable at 2–8°C for up to 3 months.
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Post-Reconstitution: Store at 2–8°C and utilize within 10-14 days.
Shipping & Documentation
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Global Logistics: Shipped in discreet, temperature-controlled packaging to maintain the structural integrity of the Selank peptide.
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Verified Quality: A batch-specific COA and HPLC/MS reports are available for every order.
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Reshipment Policy: We provide a guaranteed reshipment policy for any lost or customs-intercepted orders (terms apply).
⚠️ Research Disclaimer
Product-Specific Safety Notice: This Selank is strictly for laboratory research and analytical purposes. It is NOT intended for human or veterinary administration. All research must be conducted by qualified professionals.
Scientific Resources & References
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PubMed – NIH: Research on Selank and anxiolytic / neuroimmunomodulatory peptide activity
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National Center for Biotechnology Information (NCBI): Compound Summary – Selank (Tuftsin analogue heptapeptide: Thr-Lys-Pro-Arg-Pro-Gly-Pro)
🔍 Deep Dive Research
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[Technical Guide]: How to Reconstitute and Store Lyophilized Peptides for Maximum Potency
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[Neuroscience Study]: The Mechanism of BDNF Upregulation: Analyzing Selank in Cognitive Research










mallhorye –
Nothing to complain about.
buckj –
Good supplier.