TB-500 (Thymosin Beta-4 Fragment) – 2mg-10mg

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Price range: $46.00 through $168.00

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  • Compound: TB-500 (Thymosin Beta-4 Fragment)
  • Components: Acetyl-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser
  • Purity: ≥ 99% (Pharmaceutical Grade / HPLC & MS Tested)
  • Form: Lyophilized White Powder (Vacuum Sealed)
  • Solubility: Highly Soluble in Water (Aqueous) / Sterile Saline
  • Storage: 2-8°C (Short-term) | -20°C (Long-term / Up to 24 months)
⚠️ For Research Use Only. Not for human or veterinary applications.
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TB-500 (Thymosin Beta-4 Fragment)

TB-500 is a high-precision synthetic fragment of the naturally occurring protein Thymosin Beta-4. This specific 30-amino acid sequence is engineered to encompass the critical biological domains responsible for cellular signaling, actin sequestration, and chemotaxis. In the realm of advanced biochemical research, TB-500 is a primary focus for its role in promoting tissue repair, accelerating wound healing, and stimulating angiogenesis—the formation of new blood vessels. By interacting with G-actin, this peptide provides researchers with a stable model to study the complex mechanisms of cellular migration and extracellular matrix (ECM) remodeling.

Our TB-500 is synthesized in an ISO 9001:2015 certified and GMP-grade manufacturing environment. Utilizing state-of-the-art Solid-Phase Peptide Synthesis (SPPS) and multi-stage HPLC purification, we guarantee a chemical purity of ≥99%. This ensures that the 30-amino acid sequence is correctly assembled and free from truncated fragments or residual synthesis reagents, providing the high-fidelity data required for peer-reviewed academic and pharmaceutical studies.tb500_peptide_vial


Research Applications & Mechanisms

Actin Binding & Cellular Migration

Investigating the peptide’s ability to sequester G-actin, which influences cellular motility and the migration of regenerative cells to the site of injury.

Angiogenic Response Research

Studying the signaling pathways through which TB-500 stimulates endothelial cell differentiation and the development of new capillary networks in damaged tissues.

Connective Tissue Homeostasis

Researching the peptide’s influence on collagen deposition and the organization of the extracellular matrix during the tissue recovery process.

Inflammation Modulation

Exploring the role of Thymosin Beta-4 fragments in balancing pro-inflammatory cytokines and reducing oxidative stress in musculoskeletal research models.tb500_mechanism_infographic


Technical Specifications

Parameter Laboratory Standard
Compound TB-500 (Thymosin Beta-4 Fragment)
Full Sequence Acetyl-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser
Production Quality GMP-Level Compliance
Purity (HPLC) ≥99% (Pharmaceutical Grade)
Physical Appearance Fine, Smooth & Flat Lyophilized Cake
Molecular Weight 3341.7 Da
Solubility Highly Soluble in Water (Aqueous) / Sterile Saline
Batch Control MS & HPLC Analysis Verified

Key Features & Quality Assurance

Pharmaceutical-Grade Lyophilization

Our proprietary vacuum-sealing process ensures the TB-500 powder surface is perfectly smooth, flat, and delicate. This uniform “cake” structure guarantees rapid, clear reconstitution and prevents the 30-amino acid chain from environmental degradation.

Structural Fidelity

Every batch undergoes strict Mass Spectrometry (MS) to verify the exact amino acid sequence and sequence integrity, ensuring maximum biological activity in research environments.


Reconstitution & Storage

Reconstitution Guide

  • Preparation: Allow the vial to reach room temperature. Centrifuge for 30-60 seconds to ensure the TB-500 cake is at the base.

  • Solvent: Reconstitute with Sterile Water or Sterile Saline (0.9% NaCl).

  • Technique: Gently introduce the diluent against the vial wall. DO NOT SHAKE; swirl gently until the solution is clear and transparent.

Storage Protocols

  • Long-term: Store at -20°C (Maintains potency for up to 24 months).

  • Short-term: Stable at 2–8°C for up to 3 months.

  • Post-Reconstitution: Store at 2–8°C and utilize within 10-14 days.


Shipping & Documentation

  • Global Logistics: Shipped in discreet, temperature-controlled packaging to protect the TB-500 molecular structure.

  • Verified Quality: A batch-specific COA and HPLC/MS reports are available for every order.

  • Reshipment Policy: We provide a guaranteed reshipment policy for any lost or customs-intercepted orders (terms apply).


⚠️ Research Disclaimer

Product-Specific Safety Notice: This TB-500 (Thymosin Beta-4 Fragment) is strictly for laboratory research and analytical purposes. It is NOT intended for human or veterinary administration. All handling must be performed by qualified professionals.


Scientific Resources & References


🔍 Deep Dive Research

  • [Technical Guide]: How to Reconstitute and Store Lyophilized Peptides for Maximum Potency

  • [Regenerative Study]: The Bioactivity of Synthetic Thymic Fragments in Modern Research Models

Weight 1.1 lbs
Dimensions 327 × 375 × 265 in
Specification

2mg*10vials, 5mg*10vials, 10mg*10vials

TB-500 FAQ

What is TB-500 (Thymosin Beta-4) and its primary research application?
TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4. In laboratory research, it is primarily studied for its potent regenerative properties, specifically its ability to promote cell migration, angiogenesis (new blood vessel formation), and the repair of muscle, tendon, and ligament tissues.
What are the common synonyms and chemical names for TB-500?
TB-500 is scientifically known as Thymosin Beta-4 (Tβ4). It is often referred to as a “Regenerative Peptide” or by its sequence-related name, Ac-SDKP (though TB-500 typically refers to the full 43-amino acid sequence). Researchers search for it to study inflammatory modulation and tissue recovery.
How does TB-500 (Thymosin Beta-4) promote tissue repair in laboratory models?
In biochemical studies, TB-500 works by sequestering G-actin, which encourages cell motility and migration to injured sites. This mechanism is a key area of interest for researchers investigating accelerated healing in connective tissues and the reduction of acute inflammation.
What specifications of TB-500 peptide do you offer for wholesale?
We provide high-purity TB-500 lyophilized powder in 2mg, 5mg, and 10mg vials. These precise dosage options cater to various experimental needs, from small-scale cellular assays to more extensive animal-based regeneration studies.
What is the purity level of your TB-500 2mg, 5mg, and 10mg vials?
Our TB-500 is verified at >=99% purity through rigorous HPLC and Mass Spectrometry (MS) testing. As a leading manufacturer in China, we ensure every vial is free from impurities, ensuring consistent and reliable research data for our global clients.
Where can I buy high-quality TB-500 online for research purposes?
You can buy lab-certified TB-500 (Thymosin Beta-4) directly through our secure online store. We provide high-purity research chemicals with factory-direct pricing, fast global shipping, and discrete packaging for research institutions.
Do you offer bulk wholesale pricing for TB-500 5mg and 10mg orders?
Yes, we provide highly competitive wholesale pricing and bulk discounts for TB-500 2mg, 5mg, and 10mg vials. We are a direct-to-lab supplier, offering the best value for universities and large-scale peptide distributors worldwide.
What are the shipping and reshipment policies for international TB-500 orders?
We offer tracked global shipping for all our research peptides. To ensure a 100% secure supply chain, our “One-time Free Reshipment” policy covers any TB-500 orders that are lost or intercepted during transit, protecting your laboratory’s investment.
Is TB-500 (Thymosin Beta-4) intended for human use or athletic recovery?
Absolutely not. TB-500 is sold strictly as a Laboratory Research Chemical. It is not a drug, food, or supplement and is not intended for human or veterinary administration. It must be handled only by qualified professionals in a research setting.
Does every batch of TB-500 come with a Certificate of Analysis (COA)?
Yes, a batch-specific COA specifying the 99%+ purity, sequence identity, and quality control metrics is available upon request for every purchase of TB-500 (Thymosin Beta-4).

1 review for TB-500 (Thymosin Beta-4 Fragment) – 2mg-10mg

  1. Rated 5 out of 5

    sulyzouak

    Solid experience.

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