Pinealon
Pinealon is a high-purity synthetic tripeptide composed of the amino acids L-Glutamyl-L-Aspartyl-L-Arginine (Glu-Asp-Arg). In the field of biogerontology and neuroscience research, Pinealon is recognized as a specific bioregulator for the pineal gland and the central nervous system. Its primary mechanism involves modulating the functional activity of neurons and the production of melatonin, providing researchers with a precise tool to investigate the stabilization of circadian rhythms and the enhancement of cognitive homeostasis. Furthermore, Pinealon is studied for its ability to reduce oxidative stress and inhibit the formation of reactive oxygen species (ROS) in brain tissue models.
Our Pinealon is synthesized in an ISO 9001:2015 certified and GMP-grade manufacturing environment. Utilizing precision liquid-phase synthesis and rigorous multi-stage HPLC purification, we achieve an ultra-high chemical purity of ≥99%. This meticulous production standard ensures the peptide is free from truncated sequences and residual synthesis reagents, guaranteeing the consistency required for high-stakes research into cellular aging and neuro-endocrine signaling.
Research Applications & Mechanisms
Circadian Rhythm Regulation
Investigating the influence of Pinealon on the pineal gland’s secretory function and the restoration of normal sleep-wake cycles in experimental models.
Neuroprotective Signaling
Researching the peptide’s role in protecting neurons against hypoxia and environmental stressors, focusing on its impact on cell viability.
Antioxidant & ROS Mitigation
Studying the pathways through which the Glu-Asp-Arg sequence scavenges free radicals and reduces lipid peroxidation in cerebral tissues.
Cognitive Homeostasis
Exploring the potential of Pinealon to optimize neurotransmitter balance and study recovery mechanisms in models of chronic fatigue and neuro-degeneration.
Technical Specifications
| Parameter | Laboratory Standard |
| Compound | Pinealon (Tripeptide) |
| Sequence | Glu-Asp-Arg |
| Purity (HPLC) | ≥99% (Pharmaceutical Grade) |
| Physical Appearance | Fine, Smooth & Flat Lyophilized Cake |
| Molecular Weight | 418.4 Da |
| Concentration | Available in 5mg / 10mg vials |
| Solubility | Highly Soluble in Water (Aqueous) / Bacteriostatic Water |
| Batch Control | MS & HPLC Analysis Verified |
Key Features & Quality Assurance
Pharmaceutical-Grade Lyophilization
Our proprietary vacuum-sealing process ensures the Pinealon powder surface is perfectly smooth, flat, and delicate. This uniform “cake” structure ensures rapid, clear reconstitution and maintains the molecular integrity of the short-chain peptide during storage.
Short-Chain Stability
As a tripeptide, our Pinealon is engineered for high bio-stability and resistance to premature enzymatic breakdown, facilitating consistent observations in long-term in-vitro assays.
Reconstitution & Storage
Reconstitution Guide
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Preparation: Allow the vial to reach room temperature. Centrifuge for 30-60 seconds to ensure the Pinealon cake is at the base.
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Solvent: Reconstitute with Sterile Water or Bacteriostatic Water.
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Technique: Gently introduce the diluent against the vial wall. DO NOT SHAKE; swirl gently until the solution is clear and transparent.
Storage Protocols
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Long-term: Store at -20°C (Maintains potency for up to 24 months).
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Short-term: Stable at 2–8°C for up to 3 months.
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Post-Reconstitution: Store at 2–8°C and utilize within 10-14 days.
Shipping & Documentation
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Global Logistics: Shipped in discreet, temperature-controlled packaging to maintain the integrity of the Pinealon sequence.
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Verified Quality: A batch-specific Certificate of Analysis (COA) and HPLC/MS reports are available for every order.
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Reshipment Policy: We provide a guaranteed reshipment policy for any lost or customs-intercepted orders (terms apply).
⚠️ Research Disclaimer
Product-Specific Safety Notice: This Pinealon is strictly for laboratory research and analytical purposes. It is NOT intended for human or veterinary administration. All research must be conducted by qualified professionals.
Scientific Resources & References
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National Center for Biotechnology Information (NCBI): Compound Summary – Pinealon (Glu-Asp-Arg tripeptide neuropeptide analogue)
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PubMed – NIH: Research on Pinealon and neuroprotective tripeptides in cognitive and aging models
🔍 Deep Dive Research
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[Technical Guide]: How to Reconstitute and Store Lyophilized Peptides for Maximum Potency
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[Bioregulator Study]: The Role of Pinealon in Circadian Regulation and Brain Health Research
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