Overview
Adamax is a high-purity synthetic peptide and the most advanced iteration of the Semax family (ACTH 4-10 fragment). In the landscape of cutting-edge neuroscience, Adamax is distinguished by its unique molecular modification: the conjugation of an 1-Adamantane moiety to the C-terminus of the N-acetylated Semax chain. This strategic engineering drastically increases the peptide’s lipophilicity and resistance to enzymatic degradation, allowing for enhanced penetration across the Blood-Brain Barrier (BBB) and a significantly prolonged biological half-life compared to standard Semax or NA-Semax. Its primary mechanism of action involves the profound upregulation of Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF). Adamax provides researchers with a high-precision experimental model to investigate neuro-protection, the enhancement of synaptic plasticity, and the restoration of cognitive function in complex neurological research designs.
Our Adamax is synthesized in an ISO 9001:2015 certified environment utilizing high-precision Solid-Phase Peptide Synthesis (SPPS). We achieve an ultra-high chemical purity of ≥99%, verified by HPLC and Mass Spectrometry (MS). This rigorous production standard ensures the peptide is free from truncated sequences and residual chemical reagents, guaranteeing the consistency and structural fidelity required for long-term neurobiological assays and cognitive repair studies.
Research Applications & Mechanisms
Upregulation of BDNF & NGF
Investigating the systemic elevation of neurotrophic factors to study the peptide’s role in promoting neuronal survival and neurogenesis.
Synaptic Plasticity & Memory Research
Researching the mechanisms through which Adamax enhances Long-Term Potentiation (LTP) and investigating the molecular basis of learning and memory optimization.
Enhanced Lipophilicity & BBB Penetration
Studying the influence of the Adamantane group on the peptide’s pharmacokinetics and its role in Investigating high-efficiency neural delivery systems.
Mitigation of Neuro-Inflammation
Exploring the impact of Adamax on the brain’s inflammatory profile and its role in investigating the protection of the central nervous system from environmental stressors.
Technical Specifications
| Parameter | Laboratory Standard |
| Compound | Adamax |
| Base Sequence | N-Acetyl-Semax-Adamantane |
| Purity (HPLC) | ≥99% (Pharmaceutical Grade) |
| Physical Appearance | Fine, Smooth & Flat Lyophilized Cake |
| Modification | 1-Adamantane Base Group |
| Concentrations | Available in 5mg / 10mg vials |
| Solubility | Highly Soluble in Water (Aqueous) / PBS |
| Batch Control | MS & HPLC Analysis Verified |
Key Features & Quality Assurance
Pharmaceutical-Grade Lyophilization
Our proprietary vacuum-sealing process ensures the Adamax powder surface is perfectly smooth, flat, and delicate. This uniform “cake” structure ensures rapid, clear reconstitution and maintains the molecular stability of the modified peptide during long-term storage.
Adamantane Conjugation Verification
Every batch undergoes strict Mass Spectrometry (MS) to confirm the exact attachment of the adamantyl group, ensuring the characteristic potency and reproducible results in complex neurological signaling research.
Reconstitution & Storage
Reconstitution Guide
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Preparation: Allow the vial to reach room temperature. Centrifuge for 30-60 seconds to ensure the Adamax cake is at the base.
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Solvent: Reconstitute with Sterile Water or PBS.
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Technique: Gently introduce the diluent against the vial wall. DO NOT SHAKE; swirl gently until the solution is clear and transparent.
Storage Protocols
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Long-term: Store at -20°C (Maintains potency for up to 24 months).
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Short-term: Stable at 2–8°C for up to 3 months.
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Post-Reconstitution: Store at 2–8°C and utilize within 10-14 days for optimal results.
Shipping & Documentation
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Global Logistics: Shipped in discreet, temperature-controlled packaging to maintain the structural integrity of the Adamax peptide.
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Verified Quality: A batch-specific COA and HPLC/MS reports are available for every order.
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Reshipment Policy: We provide a guaranteed reshipment policy for any lost or customs-intercepted orders (terms apply).
⚠️ Research Disclaimer
Product-Specific Safety Notice: This Adamax is strictly for laboratory research and analytical purposes. It is NOT intended for human or veterinary administration. All research must be conducted by qualified professionals.
Scientific Resources & References
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National Center for Biotechnology Information (NCBI): ACTH Analogs and Neurotrophic Factor Research
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ScienceDirect (Elsevier): Peer-reviewed Research on Modified Semax and Synaptic Plasticity
🔍 Deep Dive Research
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[Technical Guide]: How to Reconstitute and Store Lyophilized Peptides for Maximum Potency
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[Neuro-Genetics Study]: Beyond Semax: The Adamantane Advantage in Modern Cognitive Research
reseller –
The logistics were slightly delayed, but everything else was fine.