GHRP-2
GHRP-2 (Growth Hormone Releasing Peptide-2), also known as Pralmorelin, is a high-purity synthetic hexapeptide and a potent agonist of the ghrelin receptor. In the landscape of advanced endocrine research, GHRP-2 is recognized for its superior efficiency in stimulating the pulsatile release of endogenous growth hormone (GH) from the anterior pituitary compared to its predecessor, GHRP-6. By antagonizing somatostatin and directly acting on pituitary somatotrophs, GHRP-2 provides researchers with a robust experimental model to investigate the Growth Hormone/IGF-1 axis, systemic nitrogen retention, and the molecular pathways of protein synthesis. While it retains the ability to modulate appetite centers, its orexigenic effect is significantly more controlled than first-generation secretagogues, making it a preferred tool for research focusing on lean mass homeostasis and metabolic efficiency.
Our GHRP-2 is synthesized in an ISO 9001:2015 certified environment utilizing high-precision Solid-Phase Peptide Synthesis (SPPS). We achieve an ultra-high chemical purity of ≥99%, verified by HPLC and Mass Spectrometry (MS). This rigorous production standard ensures the peptide is free from truncated sequences and residual chemical reagents, guaranteeing the consistency and structural fidelity required for high-stakes metabolic signaling studies.
Research Applications & Mechanisms
Enhanced Pulsatile GH Stimulation
Investigating the potentiation of GH pulses and the subsequent upregulation of hepatic Insulin-like Growth Factor 1 (IGF-1) in experimental models.
Nitrogen Retention & Protein Synthesis
Researching the mechanisms through which GHRP-2 promotes positive nitrogen balance and accelerates skeletal muscle repair in research designs.
Pituitary Sensitivity & Feedback Regulation
Studying the direct response of the anterior pituitary gland to GHS-R1a activation and the systemic feedback loops involving somatostatin.
Lean Mass Homeostasis & Lipid Metabolism
Exploring the influence of GHRP-2 on metabolic rate and its role in investigating the reduction of visceral adipose tissue without significant appetite disruption.
Technical Specifications
| Parameter | Laboratory Standard |
| Compound | GHRP-2 (Pralmorelin) |
| Sequence | D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2 |
| Purity (HPLC) | ≥99% (Pharmaceutical Grade) |
| Physical Appearance | Fine, Smooth & Flat Lyophilized Cake |
| Molecular Weight | 817.9 Da |
| Concentrations | Available in 5mg, 10mg, 15mg vials |
| Solubility | Highly Soluble in Water (Aqueous) / Bacteriostatic Water |
| Batch Control | MS & HPLC Analysis Verified |
Key Features & Quality Assurance
Pharmaceutical-Grade Lyophilization
Our proprietary vacuum-sealing process ensures the GHRP-2 powder surface is perfectly smooth, flat, and delicate. This uniform “cake” structure ensures rapid, clear reconstitution and maintains the molecular stability of the hexapeptide during storage.
High-Fidelity Sequence Integrity
Every batch undergoes strict Mass Spectrometry (MS) to confirm the exact amino acid sequence, ensuring maximal receptor binding affinity and reproducible results in complex hormonal signaling assays.
Reconstitution & Storage
Reconstitution Guide
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Preparation: Allow the vial to reach room temperature. Centrifuge for 30-60 seconds to ensure the GHRP-2 cake is at the base.
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Solvent: Reconstitute with Sterile Water or Bacteriostatic Water.
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Technique: Gently introduce the diluent against the vial wall. DO NOT SHAKE; swirl gently until the solution is clear and transparent.
Storage Protocols
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Long-term: Store at -20°C (Maintains potency for up to 24 months).
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Short-term: Stable at 2–8°C for up to 3 months.
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Post-Reconstitution: Store at 2–8°C and utilize within 10-14 days for optimal results.
Shipping & Documentation
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Global Logistics: Shipped in discreet, temperature-controlled packaging to maintain the structural integrity of the GHRP-2 peptide.
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Verified Quality: A batch-specific COA and HPLC/MS reports are available for every order.
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Reshipment Policy: We provide a guaranteed reshipment policy for any lost or customs-intercepted orders (terms apply).
⚠️ Research Disclaimer
Product-Specific Safety Notice: This GHRP-2 is strictly for laboratory research and analytical purposes. It is NOT intended for human or veterinary administration. All research must be conducted by qualified professionals.
Scientific Resources & References
- Comprehensive chemical, structural, and bioactivity data for GHRP-2 (Growth Hormone Releasing Peptide-2) can be accessed via PubChem.
- Curated experimental drug profile, target interaction data, and biochemical classification for GHRP-2 are available through DrugBank.
🔍 Deep Dive Research
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[Technical Guide]: How to Reconstitute and Store Lyophilized Peptides for Maximum Potency
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[Metabolic Study]: The Potency Advantage: Why GHRP-2 Leads Modern Secretagogue Research
francis –
Would recommend.