AICAR (Acadesine) Lyophilized Powder - Potent AMPK Activator for Research
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AICAR (Acadesine) – 50mg-100mg

Rated 5.00 out of 5 based on 1 customer rating
(1 customer review)

Price range: $90.00 through $172.00

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PRODUCT SPECIFICATIONS

  • Compound: AICAR (AICA Riboside / Acadesine)
  • Components: 5-Aminoimidazole-4-carboxamide Ribonucleoside (AMPK Activator)
  • Purity: ≥ 99% (Pharmaceutical Grade / HPLC & MS Tested)
  • Form: Lyophilized White Powder (Vacuum Sealed)
  • Solubility: Highly Soluble in Water (Aqueous) / DMSO / Sterile Saline
  • Storage: 2-8°C (Short-term) | -20°C (Long-term / Up to 24 months)
  • Shipping: Discrete packaging with a guaranteed reshipment policy.
⚠️ For Research Use Only. Not for human or veterinary applications.
SKU: P-AICAR Category: Tags: ,
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Overview

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide), also known as Acadesine, is a high-purity synthetic cell-permeable nucleoside. In the landscape of advanced metabolic research and exercise physiology, AICAR is distinguished by its unique ability to function as an AMPK (AMP-activated protein kinase) agonist. By mimicking the intracellular signaling of adenosine monophosphate (AMP), AICAR trick cells into a state of perceived “energy deprivation.” This triggers a systemic metabolic shift, prioritizing catabolic pathways such as fatty acid oxidation and glucose uptake while inhibiting energy-consuming anabolic processes. It provides researchers with a high-precision experimental model to investigate mitochondrial biogenesis, metabolic syndrome, and the molecular pathways of cellular endurance and insulin sensitivity.

Our AICAR is synthesized in an ISO 9001:2015 certified environment utilizing high-resolution chromatography and purification techniques. We achieve an ultra-high chemical purity of ≥99%, verified by HPLC and Mass Spectrometry (MS). This rigorous production standard ensures the compound is free from heavy metals and residual organic solvents, guaranteeing the consistency and structural fidelity required for high-stakes metabolic signaling and cardiovascular research.AICAR-Vial

Research Applications & Mechanisms

AMPK Pathway Activation

Investigating the systemic upregulation of AMPK to study its role in regulating cellular energy balance and protein kinase cascades.

Mitochondrial Biogenesis & Endurance

Researching the mechanisms through which AICAR promotes the formation of new mitochondria and investigating enhanced muscular performance in experimental models.

Glucose Uptake & Insulin Sensitivity

Studying the non-insulin-dependent pathway of glucose transport into skeletal muscle cells and its role in investigating metabolic dysfunction.

Lipid Oxidation & Adipocyte Signaling

Exploring the impact of AICAR on fatty acid mobilization and the subsequent reduction of lipid accumulation in metabolic research designs.AICAR - Mechanism of Action

Technical Specifications

Parameter Laboratory Standard
Compound AICAR (Acadesine)
Chemical Name 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside
Purity (HPLC) ≥99% (Pharmaceutical Grade)
Physical Appearance Fine, Smooth & Flat Lyophilized Cake
Molecular Weight 258.23 g/mol
Concentrations Available in 50mg / 100mg vials
Solubility Highly Soluble in DMSO / Water (Aqueous)
Batch Control MS & HPLC Analysis Verified

Key Features & Quality Assurance

Pharmaceutical-Grade Lyophilization

Our proprietary vacuum-sealing process ensures the AICAR powder surface is perfectly smooth, flat, and delicate. This uniform “cake” structure ensures rapid, clear reconstitution and maintains the molecular stability of the compound during long-term storage.

High-Precision Purity Verification

Every batch undergoes strict HPLC analysis to confirm a minimum purity of 99%, ensuring that metabolic assays are free from artifacts caused by impurities or degradation products.

Reconstitution & Storage

Reconstitution Guide

  • Preparation: Allow the vial to reach room temperature. Centrifuge for 30-60 seconds to ensure the AICAR cake is at the base.

  • Solvent: Reconstitute with DMSO (for maximum stability) or Sterile Water.

  • Technique: Gently introduce the diluent against the vial wall. DO NOT SHAKE; swirl gently until the solution is clear and transparent.

Storage Protocols

  • Long-term: Store at -20°C (Maintains potency for up to 24 months).

  • Short-term: Stable at 2–8°C for up to 3 months.

  • Post-Reconstitution: Store at 2–8°C and utilize within 7-10 days for optimal results.

Shipping & Documentation

  • Global Logistics: Shipped in discreet, temperature-controlled packaging to maintain the structural integrity of the AICAR compound.

  • Verified Quality: A batch-specific COA and HPLC/MS reports are available for every order.

  • Reshipment Policy: We provide a guaranteed reshipment policy for any lost or customs-intercepted orders (terms apply).

⚠️ Research Disclaimer

Product-Specific Safety Notice: This AICAR (Acadesine) is strictly for laboratory research and analytical purposes. It is NOT intended for human or veterinary administration. All research must be conducted by qualified professionals.

Scientific Resources & References

🔍 Deep Dive Research

  • [Technical Guide]: How to Reconstitute and Store Lyophilized Peptides for Maximum Potency

  • [Metabolic Study]: The Exercise Pill: Exploring AMPK Activation via AICAR in Modern Science

Weight 0.16 lbs
Dimensions 7.5 × 5.5 × 4 in
Specification

50mg*10vials, 100mg*10vials

Aicar FAQ

What is AICAR and its primary significance in metabolic research?
AICAR, chemically known as 5-Aminoimidazole-4-carboxamide ribonucleotide (ZMP) or Acadesine, is a potent cell-permeable activator of AMP-activated protein kinase (AMPK). In laboratory research, it is primarily investigated as an “exercise mimetic” for its ability to stimulate glucose uptake, fatty acid oxidation, and mitochondrial biogenesis in skeletal muscle models.
What are the primary synonyms and identifiers for AICAR?
AICAR is scientifically referred to as Acadesine, ZMP, or AICA Ribonucleoside. Researchers often search for AICAR 50mg or 100mg vials to conduct high-concentration studies on cellular energy homeostasis and its role in protecting tissues from ischemic injury.
How does AICAR activate the AMPK pathway in biochemical studies?
In biochemical research, AICAR is phosphorylated intracellularly into ZMP, which mimics the effects of AMP. This activation of AMPK triggers a metabolic shift toward catabolism, allowing researchers to study enhanced fat oxidation, the inhibition of protein synthesis, and the induction of cellular autophagy.
Where can I buy high-purity AICAR 50mg or 100mg online for lab research?
You can buy lab-certified AICAR directly through our secure platform. We offer high-purity AICAR 50mg and 100mg vials at competitive prices, providing biotech firms and research institutions with premium-grade metabolic modulators and reliable global tracked shipping.
What purity level is guaranteed for your AICAR 50mg and 100mg research vials?
We guarantee a verified purity of >=99% for all our AICAR batches, confirmed via HPLC and analytical testing. As a leading manufacturer in China, our commitment to high-purity chemical retail and wholesale ensures that your metabolic research is supported by consistent and reliable chemical integrity.
Do you offer low-price wholesale options for bulk AICAR 100mg orders?
Yes, we provide highly competitive low-price wholesale AICAR for large-volume purchases. Our factory-direct model allows us to offer the most cost-effective tiered pricing for universities and global distributors looking for a reliable source for wholesale AICAR 100mg vials.
What are the recommended storage protocols for AICAR 100mg lyophilized powder?
For long-term stability, AICAR should be stored at -20°C in a dry environment. After reconstitution with sterile diluent (such as PBS or DMSO) for laboratory assays, the solution should be kept refrigerated at 2-8°C. Protecting the vials from heat and direct sunlight is essential for maintaining research integrity.
What is your shipping and reshipment policy for international AICAR orders?
We offer tracked and secured global shipping for all our research chemicals. Our “One-time Free Reshipment” policy covers any AICAR orders lost or intercepted during transit, providing a risk-free procurement experience for those looking to buy high-purity metabolic activators internationally.
Is AICAR (Acadesine) intended for human athletic performance or bodybuilding?
Absolutely not. AICAR is sold strictly as a Laboratory Research Chemical. It is not a drug, food, or supplement and is not intended for human or veterinary administration. Misuse of AMPK activators for performance enhancement is strictly prohibited in regulated sports.
Does every shipment of AICAR 100mg come with analytical documentation?
Yes, every purchase of AICAR includes a batch-specific Certificate of Analysis (COA). This document confirms the 99%+ purity, molecular weight, and quality metrics required for formal scientific validation and high-level metabolic research.

1 review for AICAR (Acadesine) – 50mg-100mg

  1. Rated 5 out of 5

    abraham.diazm –

    Shipping was quicker than expected.

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